Emily Mills BSc(Hons), PhD

I completed my PhD at the University of Sydney, Australia, under the supervision of Professor Luke Henderson and Dr. Flavia Di Petro. My PhD focused on the use of resting state fMRI to investigate the function of brainstem pain-modulation circuits in individuals with chronic orofacial pain. I commenced my post-doctoral fellowship with Professor Karen Davis at the Krembil Brain Institute in June 2021. My current research aims to use advanced modeling of diffusion MRI to understand structural brain alterations in individuals with chronic neuropathic pain, and to assess whether pre-treatment white matter structure can predict treatment effectiveness.



Principal Hospital Appointment:

Toronto Western Hospital


Karen Davis

Key Publications:

Crawford, L. S., Mills, E. P., Hanson, T., Macey, P. M., Glarin, R., Macefield, V. G., … & Henderson, L. A. (2021). Brainstem mechanisms of pain modulation: a within-subjects 7T fMRI study of placebo analgesic and nocebo hyperalgesic responses. Journal of Neuroscience, 41(47), 9794-9806. El-Sayed, R., Fauchon, C., Kim, J. A., Firouzian, S., Osborne, N. R., Besik, A., Mills, E. P., Bhatia, A., & Davis, K. D. (2021). The Potential Clinical Utility of Pressure-Based vs. Heat-Based Paradigms to Measure Conditioned Pain Modulation in Healthy Individuals and Those With Chronic Pain. Frontiers in Pain Research, 2. Mills, E. P., Keay, K. A., & Henderson, L. A. (2021). Brainstem Pain-Modulation Circuitry and Its Plasticity in Neuropathic Pain: Insights From Human Brain Imaging Investigations. Frontiers in Pain Research, 2, 34. Mills, E. P., Akhter, R., Di Pietro, F., Murray, G. M., Peck, C. C., Macey, P. M., & Henderson, L. A. (2021). Altered Brainstem Pain Modulating Circuitry Functional Connectivity in Chronic Painful Temporomandibular Disorder. The Journal of Pain, 22(2), 219–232. Mills, E. P., Alshelh, Z., Kosanovic, D., Di Pietro, F., Vickers, E. R., Macey, P. M., & Henderson, L. A. (2020). Altered Brainstem Pain-Modulation Circuitry Connectivity During Spontaneous Pain Intensity Fluctuations.?Journal of Pain Research,?13, 2223.