The link between pain and memory in the medial temporal lobe
The medial temporal lobe (MTL) is primarily thought to be responsible for memory and cognition. However, several functional neuroimaging studies have shown the involvement of this brain region in both the response to experimental pain in healthy individuals and in patients with chronic pain.
Defining and Predicting Pain Volatility in Users of the Manage My Pain App: Analysis Using Data Mining and Machine Learning Methods
The advent of technology and mobile health apps has transformed the way people monitor, manage, and communicate health-related information. For pain, “Manage My Pain” is a mobile health app used by thousands of individuals to measure and manage their pain.
Gabapentin increases expression of subunit-containing GABAA receptors
Gabapentin (also known as Neurontin) is clinically prescribed for the treatment of seizures, pain, and anxiety. While gabapentin is known to modulate voltage-gated calcium channels, some studies have suggested the effects of gabapentin are also dependent on GABAergic inhibition.
Conditioned pain modulation is not unidirectional: both hyper- and hypoalgesia can arise depending on the stimulus
Conditioned pain modulation (CPM) is the phenomenon in which one painful stimulus (the conditioning stimulus) affects the pain perception of a second stimulus (the test stimulus) at a different site.